MSNBC’s “Morning Joe” co-host Mika Brzezinski once again maligned President Donald Trump’s mental health when she urged the nation on Wednesday “to start thinking 25th Amendment” and work toward removing Trump from office.

“At some point, you are working for a president who is not fit to lead, who is going to do something crazy in five minutes, one hour, tonight or tomorrow,” Brzezinski said, directing her comments toward Trump administration members.

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“What more do you need to hear from him to start thinking 25th Amendment or something else?” she asked. “This is not OK. This is not normal. And this is where we are.”

Brzezinski’s latest in a long line of concerns regarding Trump’s mental health arose after the president targeted porn star Stormy Daniels in a tweet on Tuesday. Daniels, who is represented by celebrity lawyer Michael Avenatti, claims to have had an affair with Trump during his marriage to first lady Melania Trump.

Trump jubilantly tweeted after a judge dismissed Daniels’ defamation case against Trump and his former lawyer, Michael Cohen.

“‘Federal Judge throws out Stormy Danials [sic] lawsuit versus Trump. Trump is entitled to full legal fees.’ @FoxNews Great, now I can go after Horseface and her 3rd rate lawyer in the Great State of Texas. She will confirm the letter she signed! She knows nothing about me, a total con!” Trump wrote.

Daniels responded on Twitter, writing, “Ladies and Gentlemen, may I present your president. In addition to his … umm … shortcomings, he has demonstrated his incompetence, hatred of women and lack of self control on Twitter AGAIN! And perhaps a penchant for bestiality. Game on, Tiny.”

Invoking the 25th Amendment allows for the removal of a president from office if that person is temporarily physically or mentally unable to carry out his or her constitutional duties. And Brzezinski — who has speculated about Trump’s mental fitness with her co-host, Joe Scarborough, countless times — renewed her charges.

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“Look, women and men should not behave this way, and we should call it out. Actually, for me, this is one of the many, many, many ways this president has shown us that he is not fit, possibly not even well,” Brzezinski said before targeting Trump administration members for serving their country.

Related: ‘Morning Joe’ Slams ‘Bumbling Idiot’ Trump Over Journalist’s Disappearance

“And I don’t understand the people in this administration taking matters into their own hands and trying to sort of stick it out because they can keep things together,” she bemoaned. “On the foreign-policy front, [Trump] is cratering our reputation. He is making us an international joke.”

“We are losing our influence because this is the type of man who calls a woman a ‘horseface.’ By the way, a woman he chose to have sex with,” Brzezinski added, suggesting that Trump uses words like “horseface” because the Russians must have some dirt on him.

“That’s sort of sad and disturbed. And you just wonder what could the Russians have on him if he is this base and animalistic and disgusting,” she insisted.